Description:

Differential dependency network (DDN) is a caBIG® (cancer Biomedical Informatics Grid) analytical tool for detecting and visualizing statistically significant topological changes in transcriptional networks representing two biological conditions. Developed under caBIG®'s In Silico Research Centers of Excellence (ISRCE) Program, DDN enables differential network analysis and provides an alternative way for defining network biomarkers predictive of phenotypes. DDN also serves as a useful systems biology tool for users across biomedical research communities to infer how genetic, epigenetic or environment variables may affect biological networks and clinical phenotypes. Besides the standalone Java application, we have also developed a Cytoscape plug-in, CytoDDN, to integrate network analysis and visualization seamlessly.

Changes to previous version:

Initial Announcement on mloss.org.

BibTeX Entry: Download

Corresponding Paper BibTeX Entry: Download

Supported Operating Systems: Linux, Windows, Mac Os X

Data Formats: Csv

Tags: Visualization, Lasso, Cytoscape, Differential Network, Graphical Model, Ddn

Archive: download here

Comments

No one has posted any comments yet. Perhaps you'd like to be the first?

Leave a comment

You must be logged in to post comments.