Project details for FABIA

Logo FABIA 1.0.0

by hochreit - July 28, 2010, 17:17:16 CET [ Project Homepage BibTeX BibTeX for corresponding Paper Download ]

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Description:

Biclustering by "Factor Analysis for Bicluster Acquisition" (FABIA). FABIA is a model-based technique for biclustering, that is clustering rows and columns simultaneously. Biclusters are found by factor analysis where both the factors and the loading matrix are sparse. FABIA is a multiplicative model that extracts linear dependencies between samples and feature patterns. It captures realistic non-Gaussian data distributions with heavy tails as observed in gene expression measurements. FABIA utilizes well understood model selection techniques like the EM algorithm and variational approaches and is embedded into a Bayesian framework. FABIA ranks biclusters according to their information content and separates spurious biclusters from true biclusters. The code is written in C++ based on Rcpp package.

Changes to previous version:

Initial Announcement on mloss.org.

BibTeX Entry: Download
Corresponding Paper BibTeX Entry: Download
URL: Project Homepage
Supported Operating Systems: Platform Independent
Data Formats: Any Format Supported By R
Tags: Bioinformatics, Clustering, Bioconductor, Matrix Factorization, Sparse Learning, Variational Inference, Biclustering, Gene Expression
Archive: download here

Other available revisons

Version Changelog Date
2.8.0

CHANGES IN VERSION 2.8.0

NEW FEATURES

o rescaling of lapla
o extractPlot does not plot sorted matrices

CHANGES IN VERSION 2.4.0

o spfabia bugfixes

CHANGES IN VERSION 2.3.1

NEW FEATURES

o Getters and setters for class Factorization

2.0.0:

  • spfabia: fabia for a sparse data matrix (in sparse matrix format) and sparse vector/matrix computations in the code to speed up computations. spfabia applications: (a) detecting >identity by descent< in next generation sequencing data with rare variants, (b) detecting >shared haplotypes< in disease studies based on next generation sequencing data with rare variants;
  • fabia for non-negative factorization (parameter: non_negative);
  • changed to C and removed dependencies to Rcpp;
  • improved update for lambda (alpha should be smaller, e.g. 0.03);
  • introduced maximal number of row elements (lL);
  • introduced cycle bL when upper bounds nL or lL are effective;
  • reduced computational complexity;
  • bug fixes: (a) update formula for lambda: tighter approximation, (b) corrected inverse of the conditional covariance matrix of z;

1.4.0:

  • New option nL: maximal number of biclusters per row element;
  • Sort biclusters according to information content;
  • Improved and extended preprocessing;
  • Update to R2.13
October 18, 2013, 10:14:57
2.4.0

CHANGES IN VERSION 2.4.0

o spfabia bugfixes

CHANGES IN VERSION 2.3.1

NEW FEATURES

o Getters and setters for class Factorization

2.0.0:

  • spfabia: fabia for a sparse data matrix (in sparse matrix format) and sparse vector/matrix computations in the code to speed up computations. spfabia applications: (a) detecting >identity by descent< in next generation sequencing data with rare variants, (b) detecting >shared haplotypes< in disease studies based on next generation sequencing data with rare variants;
  • fabia for non-negative factorization (parameter: non_negative);
  • changed to C and removed dependencies to Rcpp;
  • improved update for lambda (alpha should be smaller, e.g. 0.03);
  • introduced maximal number of row elements (lL);
  • introduced cycle bL when upper bounds nL or lL are effective;
  • reduced computational complexity;
  • bug fixes: (a) update formula for lambda: tighter approximation, (b) corrected inverse of the conditional covariance matrix of z;

1.4.0:

  • New option nL: maximal number of biclusters per row element;
  • Sort biclusters according to information content;
  • Improved and extended preprocessing;
  • Update to R2.13
December 20, 2012, 14:20:58
2.0.0

2.0.0:

  • spfabia: fabia for a sparse data matrix (in sparse matrix format) and sparse vector/matrix computations in the code to speed up computations. spfabia applications: (a) detecting >identity by descent< in next generation sequencing data with rare variants, (b) detecting >shared haplotypes< in disease studies based on next generation sequencing data with rare variants;
  • fabia for non-negative factorization (parameter: non_negative);
  • changed to C and removed dependencies to Rcpp;
  • improved update for lambda (alpha should be smaller, e.g. 0.03);
  • introduced maximal number of row elements (lL);
  • introduced cycle bL when upper bounds nL or lL are effective;
  • reduced computational complexity;
  • bug fixes: (a) update formula for lambda: tighter approximation, (b) corrected inverse of the conditional covariance matrix of z;

1.4.0:

  • New option nL: maximal number of biclusters per row element;
  • Sort biclusters according to information content;
  • Improved and extended preprocessing;
  • Update to R2.13
November 10, 2011, 17:09:15
1.4.0

New option nL: maximal number of biclusters per row element; Sort biclusters according to information content; Improved and extended preprocessing; Update to R2.13

July 15, 2011, 14:42:00
1.0.0

Initial Announcement on mloss.org.

July 28, 2010, 17:17:16

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